Genomics & Systems Biology
Using Precision Medicine tools to unmask and address biological determinants of cancer health disparities.
Global Oncology Disparities
Genetic Ancestry
Biological Determinants
“….in certain minority groups, such as African Americans, in the United States, the family health history is very incomplete, as is the relatedness of individuals through a pedigree analysis that would extend beyond three generations, for instance, in contemporary families. … we have a disconnection of information… that can be overcome with global genomic oncology” - M. Davis (Scientific Director of ICSBCS)
We are poised to make exceptional contributions to cancer research and expand knowledge of disease diversity .
THE POWER OF INCLUSION…. TO DEFINE PLASTICITY (variation)
Under my direction, our ICSBCS teams’ research initiatives, have exceeded all expectations! We have succeeded with integrating diverse biospecimen types into our prospective and retrospective cohorts of over 5000 cases and controls. We are currently banking biospecimen for tumor, circulating biomarkers and germline DNA; including peripheral blood, fresh tumor/normal tissue, saliva (germline DNA) and patient derived organoids. By expanding our reach into each region of Africa, with formal collaborations in over a dozen sites across Africa and the West African diaspora, we are poised to make exceptional contributions to cancer research, expanding current knowledge of ancestral susceptibility in cancer risk, diversity in tumor pathology and precision treatment effectiveness in African descendant populations.